CAS 25895-60-7 Sodium cyanoborohydride Cyanoborohydrure de sodium

General description

Sodium cyanoborohydride is a versatile reducing agent stable in aqueous solution at pH 7.2. It is a weaker reducing agent as compared to NaBH4. It effectively reduces Schiff bases. NaCNBH4 participates in the reductive methylation for the efficient and selective conversion of the e-amino groups of lysyl residues in proteins to the mono- and dimethyl derivatives.

CAS 25895-60-7 Sodium cyanoborohydride

Product Description
Product Name Sodium cyanoborohydride
CAS NO 25895-60-7
Molecular Formula CH3BNNa
Molecular Weight 62.84
EINECS 247-317-2
Melting Point >242 °C (dec.) (lit.)
Boiling Point 307°C
Flash Point −1 °F
Density 1.083 g/mL at 25 °C
Grade Pharmaceutical Grade
Solubility Soluble in water (100 mg/ml, with heating), methanol, ethanol, and THF. It is insoluble in nonpolar solvents such as benzene or hexane
Appearance Powder
Storage Store below +30°C
Product details
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General description

Sodium cyanoborohydride is a versatile reducing agent stable in aqueous solution at pH 7.2. It is a weaker reducing agent as compared to NaBH4. It effectively reduces Schiff bases. NaCNBH4 participates in the reductive methylation for the efficient and selective conversion of the e-amino groups of lysyl residues in proteins to the mono- and dimethyl derivatives.

Application

Reactant for:

  • Direct conversion of heterocyclic aldehydes to esters (oxidizing behavior)
  • Reductive amination reactions
  • Intramolecular reductive cyclization reactions
  • Reductions reactions
  • Preparation of dicyanoborate-based ionic liquids as hypergolic fluids for bipropellants

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